Pemetrexed – Oncology Drug Information Alimta is a novel antifolate compound with inhibitory activity against a number of enzymes including thymidilate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyl transferase. Alimta has been studied with cis-platinum (Cisplatin) or gemcitabine (Gemzarâ) in the treatment of non-small-cell lung cancer (NSCLC). Phase II...