Primal Defense Probiotic Formula

Primal Defense contains probiotics that support your guts flora balance, promotes consistent bowel function, controls stomach acid levels to quickly eliminate burning in the stomach and maintains your immune system, all of which are necessary to support your overall health. Total health begins in the gut, so an optimized digestive tract has an overabundance of health benefits.

The probiotics in Primal Defense maximize the benefits of a healthy diet by supporting normal absorption and assimilation of nutrients in the gut.

The only probiotic that contains the dynamic benefits of HSOs™ (Homeostatic Soil Organisms).

If you were to take only one product for your health supplement needs, this one probiotic formula should be that one supplement! The benefits are hugh and we all need a little more “real” in our lives and a few less chemically enhanced toxic substitutes.

primal defense powder and caplets
Primal Defense – Nature’s First Probiotic

Powder & Caplets

  • Provides 14 Probiotic Strains
  • Grown in a base of Nutrient-Rich Superfoods
  • Over 100 naturally occurring Vitamins, Minerals & Live Enzymes
  • Utilizes Exclusive Poten-Zyme™ and UltraZorbe™ Delivery Systems
  • Requires No Refrigeration
  • Order Today: Ultimate Probiotic


What is Primal Defense ?

Primal Defense is a whole food probiotic blend containing 14 strains of hardy plant based, non-dairy HSOs™ (Homeostatic Soil Organisms.) HSOs™ contain naturally occurring live enzymes, vitamins and minerals designed to optimize the digestive terrain, bowel and immune system function. These unique micro-organisms are shown to devour undigested matter, and eliminate yeast, parasites and bad bacteria from the intestines. Primal Defense contains the same nutrients used for thousands of years by some of the healthiest and longest living people in the world.

Why do you need Primal Defense?

bacteria in intestines Primal Defense HSOBeneficial soil and plant based microbes used to be ingested through food grown in rich, unpolluted soil. However, for the last 50 years our soil has been sterilized with pesticides and herbicides, destroying most bacteria, both bad and good. Our modern lifestyle, which includes antibiotics, chlorinated water, agricultural chemicals, pollution and poor diet, is responsible for eradicating much of the beneficial bacteria in our bodies. A lack of beneficial microorganisms often results in poor intestinal and immune system health, contributing to a wide range of symptoms and illnesses.


The following symptoms and conditions may result from a lack of probiotics:

  • Crohns Disease Symptoms
  • Gas, Bloating and Indigestion (Gastritis)
  • IBS (Irritable Bowel Syndrome)
  • Diarrhea and/or Constipation
  • Skin problems such as Acne, Eczema & Psoriasis
  • Bad Breath and Body Odor
  • Delayed development in children
  • Candida Yeast Infections
  • High Cholesterol Levels
  • Chronic Fatigue & Fibromyalgia
  • Frequent Colds and Flu

What are HSOs (Homeostatic Soil Organisms)?

The main component in Primal Defense is HSOs™, which have been used for over 22 years by thousands of health care practitioners. The non-mutated naturally occurring colonies of probiotics are from the original, pristine cultures found in unpolluted soil and plants, now cultivated in U.S. laboratories using proprietary methods. The HSOs™ are in a substrate of nutrient rich superfoods providing vitamins, minerals, trace elements, enzymes and proteins. The probiotics are then made dormant using the Microflora Delivery System™, which protects and delivers them directly to the GI tract where they multiply and flourish.

How do HSOs work?

Impervious to stomach acids and the digestive process, the microorganisms move through the stomach into the intestinal tract where they form colonies along the intestinal walls. HSOs™ multiply in the intestines and actually compete with harmful bacteria and yeasts for receptor sites, crowding out pathogens and taking up residence. Once established, the organisms quickly begin producing the proper environment for nutrient absorption, thus reinstating a balanced pH.

According to early research and anecdotal evidence, the following is a summary of the actions of HSOs™ .

  • Work from inside the intestines dislodging accumulated decay from the walls and flushing out waste.
  • Breaks down hydrocarbons, a unique ability to split food into its most basic elements allowing almost total absorption through the digestive system. This increases overall nutrition and enhances cellular development.
  • Produce specific proteins that act as antigens, encouraging the immune system to manufacture huge pools of uncoded antibodies. This increased production of antibodies may significantly boost the body’s ability to ward off disease.
  • Very aggressive against pathological molds, yeasts, fungi, bacteria, parasites and viruses.
  • Works in symbiosis with somatic (tissue or organ) cells to metabolize proteins and eliminate toxic waste.
  • Stimulate the body to produce natural alpha-interferon, a potent immune system enhancer and powerful virus inhibitor.
  • Provides critical Lactoferrin supplementation as a by-product of their metabolism. Lactoferrin is an iron binding protein essential for retrieving iron from foods.

What is the difference between Primal Defense and other probiotics?

Even if they manage to get through the destructive stomach acids, most probiotic supplements can have a difficult time implanting in colons that are pH imbalanced or have too many harmful bacteria. HSOs™ are designed to implant in any colonic environment. The Microflora Delivery System™ensures that the probiotics colonize throughout the digestive tract where they are most effective. The probiotics contained in Primal Defense™ are grown and incorporated into a living whole food substrate using the Poten-Zyme™ process, which allows them to thrive on their long journey through the GI tract.

Most probiotics on the market today grow bacteria, and then in a centrifuge, separate them from their substrate. We believe the substrate is as important as the probiotics themselves. Many probiotics have included fructooligosaccharides (FOS) in their product. FOS is an indigestible sugar that may cause digestive disturbances in certain individuals. Primal Defense™ contains no FOS.

Since most probiotic supplements contain live cultures, they are temperature and age sensitive, therefore requiring refrigeration. If room temperature can begin to degrade these probiotics, imagine what the warm human body will do. Our HSOs™ remain dormant until activated by body fluids, thus requiring no refrigeration. Many probiotic products measure their potency in colony forming units (CFU), whereas in Primal Defense™, it’s not the quantity of probiotics, it’s the quality. The hardy probiotic strains in Primal Defense™ are resistant to heat, cold, stomach acid, chlorine, fluorine, ascorbic acid and bile. The efficacy of a probiotic should be based upon its ability to ferment foods.

What are physicians saying about Primal Defense?

“I use quite a bit of Primal Defense™ for tough cases of bowel toxemia and irritable bowel syndrome. My patients like it, and I attest to Primal Defense™ being a superior product for gut metabolism.”
-James Privatera, MD

“Almost all people who consult me for the care of irritable bowel syndrome, candidacies, Lyme disease, or infections get their gut flora changed to healthier consistencies by my prescribing Primal Defense™ for them. I am invariably using one of the lactobacillus preparations, and the HSOs™ in Primal Defense™ as the top of the line, the Cadillac of lactobacilli.”
-Seldon Nelson, DO

“For many years now, I have been involved in alternative medical care and integrated medicine. In the search for effective, safe remedies, I am constantly reviewing product claims and anecdotal reports. More often than not they fail to meet my expectations, that is, except for Primal Defense™. This product generated the most affirmative response I have ever seen.”
-Charles Hamel, MD

As a mother and physician, I am enthusiastic about Primal Defense as a treatment for autism. Children with this disorder do not have normal gut functioning. Often they are infected with Candida and clostridium, and fail to develop normally. If parents would put their little patients on a dairy-free diet and also supplement with Primal Defense™, much improvement in their communication skills would occur and many autistic symptoms would disappear. This happened for my son.”
-Natasha Campbell-McBride, MD

“I believe Primal Defense™ is applicable as a food supplement for everyone, whether a person is sick or not. Where people specifically find advantages in using Primal Defense™ is in situations involving chronic disease of gut origin. Since my
expertise lies in the area of gastrointestinal disorders, this product is the primary therapy that I utilize on a routine basis. People with arthritis, chronic constipation, Crohn’s disease, colitis, and other gut-linked systemic conditions improve by supplementing with Primal Defense™.”
-Joseph Brasco, MD, Board Certified Gastroenterologist

“One of my patients had exceedingly elevated blood triglycerides at 305 milligrams per deciliter (mg/dl). Six weeks later, after taking the soil organisms, her triglycerides dropped to a mere 151 mg/dl. I’m excited about the product. There are many positive experiences associated with it.”
-Phyllis Wilson Confer, DC

Two Primal Delivery Systems

Primal Defense comes in two easy to use forms: powder and UltraZorbe™ caplets. UltraZorbe™ caplets (Ultra-absorption) utilize a proprietary technology that fully preserves the delicate probiotics and enzymes in the product without the use of heat. UltraZorbe™ caplets are designed to rapidly disintegrate and dissolve thus delivering the nutrients in the most efficient and effective manner. Just drop a few caplets in water and see for yourself.

Cultured with the following:

  • Lactobacillus Acidophilus Lactobacillus Leichmannii
  • Lactobacillus Bulgaricus Lactobacillus Lactis
  • Lactobacillus Plantarum Lactobacillus Caseii
  • Lactobacillus Brevis Bifidobacteria Bifidum
  • Lactobacillus Caucasicus Saccharomyces Boulardii **
  • Lactobacillus Fermenti Bacillus Subtilis
  • Lactobacillus Helveticus Bacillus Lichenformis

Primal Defense™ is a natural whole food probiotic blend of HSOs™ (Homeostatic Soil Organisms) utilizing the Poten-Zyme™ process and the Microflora Delivery System™. Primal Defense™ contains naturally occuring enzymes, vitamins, minerals, amino acids, antioxidants and phyto sterols/sterolins.
** A lactic acid yeast that does not promote the growth of Candida.

How to take Primal Defense Ultrazorbe Caplets

How Many / How Long. This is a therapeutic product. Proceed gradually. Primal Defense begins to clean out toxins and pathogens right away. However, if you increase too quickly, the cleansing will occur faster than the body can eliminate the accumulated toxins. This may cause some discomfort (see “What to Expect When Taking Primal Defense Ultrazorbe Caplets”)

  1. How many: Start with one 900mg caplet per day and work up to a minimum of six per day for an average of about three months. This is done by taking one caplet for the first few days, two for the next few days, etc. People with severe problems may want to work up to and stay on a higher dosage longer. The therapeutic dosage for chronic or problematic illness is an average of twelve 900mg. caplets per day. During the three month period you will saturate your body with beneficial bacteria and allow the immune system functions to react. After three months or so you can gradually decrease back to the recommended maintenance serving of three caplets per day (one bottle per month).
  2. Water: Drink plenty of water: 8-10oz of only distilled or reverse-osmosis filtered water.
  3. When to take: Primal Defense is most effective when taken on a timed schedule. It is best to take the product 2-3 times per day equally spaced out by time. Take on an empty stomach at least 1/2 hour before meals, first thing in the morning or before bedtime.

Prohibitions. The following prohibitions should be observed:

  1. NO CHLORINATED WATER. Chlorine can kill beneficial bacteria in the body. Use distilled or reverse osmosis filtered water only. Drinking chlorinated water once in a while (such as in a restaurant) is OK
  2. NO HARSH HERBAL COLON CLEANSES. These may be too invasive and interfere with the bacterial balance. If constipation occurs take a mild herbal laxative. HSOs cleanse the colon of putrefaction and balance colonic bacteria environment. This is generally accomplished in a gentle, systematic manner.
  3. COLON HYDROTHERAPY (physical cleanses, water only, no oxygen) is an excellent method of removing die-off bacteria parasites, and also to remove broken up mucoid (putrefaction)
  4. NO PARASITE KILLERS. Primal Defense and olive leaf extract will assist the body with the elimination of parasites, both regular and amoebic. Some herbal parasite killers may interfere with soil organisms ability to colonize.
  5. ANTIBIOTIC DRUGS. It is believed that antibiotics MAY kill much of the bacteria in the GI track, although some strains may survive. There’s no definitive research on this subject. The developing biochemist recommends continuing to take Primal Defense (as far apart from the antibiotic ingestion as possible) and increasing the dosage after the antibiotics. Do not take Primal Defense within several hours of other medications.

LIFESTYLE ADJUSTMENTS. Many things we do in our daily life affect our bacterial balance, absorption, and immune system. The following adjustments are suggested to increase your body’s positive respons

  1. DECREASE COFFEE consumption. The acid in coffee will interfere with the bacterial environment. Try to consume no more than 1 cup per day.
  2. DECREASE SUGAR and CARBOHYDRATES (including pasta). These feed parasites and yeast / fungi and can cause imbalances leading to diabetes and other abnormal conditions. Most of us have yeast and fungus overgrowth. Although Primal Defense will deal with this over time, why feed the pathogens if you don’t have to? Many people report a decrease in sugar / carbohydrate cravings after being on the product for several months.
  3. INCREASE FRESH FRUIT and VEGETABLE consumption. This will facilitate good elimination. Try our concentrated whole food product PERFECT FOOD. It is the nutritional equivalent of 5-10 servings of organic vegetables and the Vitamin C equivalent of 2 servings of fruit (per 2 level tablespoons) There are no fillers and no herbs in Perfect Food, and people who use it report increased energy and better elimination.
  4. INCREASE WATER consumption. You should be drinking at least eight 8-oz glasses of good water (not juice) a day on an empty stomach. Water helps flush toxins from the body to prevent re-absorption.

OTHER SUPPLEMENTS OR MEDICATION. Increase absorption. This means everything you ingest, including supplements, drugs and food, will be absorbed and assimilated better. You will need to monitor any medication, such as insulin and blood pressure medicine, to insure that you are not taking too much. Vitamins, minerals, antioxidants and whole food supplements (such as greens) are fine. Many people can eliminate enzyme supplements. Primal Defense is enzymatic in action especially when taken before meals. Primal Defense can replace other probiotics. Primal Defense contains ocean phytoplanktons (similar to blue/green algae) that contain over 70 micronutrients. These micronutrients are easily absorbed, providing a good base of trace minerals, proteins, and enzymes.


What Are Beneficial Bacteria? The beneficial microorganisms in the Primal Defense are multiple strains of beneficial “transient” and “resident” bacteria. Our bodies do not manufacture soil bacteria; we used to ingest them every day with unpolluted food from rich non-chemical soil. Since it is difficult to get unpolluted food or soil any more, and we live a lifestyle that kills off much of the good bacteria in our bodies, we have to supplement our diet every day with these organisms. “Resident” bacteria such as acidophillus can only proliferate when we eat the right living foods, our colons are not overrun with yeast or pahogenic bacteria, and our colonic pH is slightly acidic. Beneficial bacteria have multiple function in our bodies. One is to cleanse the rotting layers of undigested hydrocarbons lining our digestive system (including the small intestine); another is to trigger the immune system to create extra immune-bolstering chemicals and extra antibodies (B-lymphocytes). These vigorous antibodies travel the body searching out pathogens or foreign matter, and the increased immune function helps eliminate parasites as well as bacteria, viruses, fungi, and yeasts that are in the body actively or left over from previous illnesses. A fight then begins between the revitalized immune system and the pathogenic invaders that will cause a “die-off” (detoxification).

90-Day Program. “Good” bacteria in our intestines are responsible for keeping the “bad” bacteria in check to establish proper balance in the GI tract. Because most of us have putrefaction and bad bacteria, the friendly bacteria in Primal Defense must battle overwhelming odds to crowd out pathogens and have enough left over to provide the immune system with the proper stimulus. THIS NATURAL RESTORATION PROCESS TAKES TIME. You didn’t arrive at your current health state overnight. If you are taking the product because you have a health problem, DO NOT EXPECT TO SEE OVERNIGHT RESULTS. BE PREPARED TO COMMIT TO A MINIMUM OF 90 DAYS at the recommended dosage.

Toxin Elimination. Your body may go through a “Healing Opportunity” period. As the body cleanses and repairs itself, toxins MUST BE PURGED from the body. For example, a “cold” is not “the sickness”, a cold is the process by which your body eliminates the toxins after the fact. Many people have very few or mild toxin-elimination responses. But some MAY go through what is known as a “Herxheimer Reaction” when the body goes through a bout of what is or has been a symptom of illness. In homeopathy, it is commonly assumed a Herxheimer Reaction is a desired signal meaning the treatment is working. Symptoms of a prior condition repeating for a period of time are called “retracing”. If you do experience a “healing opportunity”, Don’t PANIC, THIS IS NORMAL! The HSO’s in Primal Defense are not making you sick. The yeast, fungi, harmful bacteria, parasites or viruses in your body are reacting to your body’s own cleansing process.

Many people, when they understand why they may get a reaction, welcome any temporary discomfort they might experience as evidence of the cleansing and healing process. This discomfort is usually short and mild, from several hours to a day or two depending on the individual. For example, a person with allergies may go through an allergic period with headaches, stuffed nose, etc. Someone with chronic fatigue may go through a short time of exhaustion or weakness. A period of constipation is common as putrefaction is being pulled from the colon.

Bowel Function. If you’ve had constipation for a long time, you may have bouts of constipation while the digestive system goes through the normalization process, especially at the higher levels of Primal Defense. Increased constipation is a result not merely of lack of fiber but absence of the good bacteria necessary for enzymatic action on the food. Primal Defense will help your body regulate the elimination process. THIS WILL TAKE TIME. Eat more fresh fruits and vegetables to aid in the process and take a good green drink (try our “Perfect Food” organic whole food powder) as a supplement. If at any time you become too uncomfortable, decrease the dosage (i.e. if you are taking 6 caplets, back down to 3 or 4.) Do no be alarmed if your stools become very dark. This is the putrefaction being eliminated.

Headaches, Sore Throat, Body Aches, Allergic Symptoms, Runny Nose, Phlegm, Pimples or Skin Rashes, Flu-like Symptoms. These are regarded as classic symptoms of detoxification of the body. Rarely will these reactions cause much discomfort; often they last for only several hours and sometimes several days. Poisons have to come out of the body somewhere, and usually come out in the weakest areas. If one has had pneumonia or lung problems, often he will experience mucous and phlegm coughed up from the lungs. Sinus problems often result in headaches as the toxins are being eliminated through the digestive system. DRINK AT LEAST 8 GLASSES OF NON-CHLORINATED WATER DAILY. This will help flush the toxins out of the system.

Yeast and Fungus. Primal Defense is extremely aggressive against yeast and other fungi. If you have this problem, start by taking a small amount (1/2 caplet) and gradually increase to 9 to 12 per day. Many people experience yeast elimination very quickly. Sometimes this process takes several months. You may go through some sugar/carbohydrate cravings or even mild depression and tiredness. THIS IS NORMAL and will pass. If you get fecal tests, do not be surprised if more yeast or “bad” bacteria show up in your stool in the first several months. They have to come out somewhere! Because this elimination can be very quick or heavy, proceed conservatively.

Discomfort. IF AT ANY TIME YOU FEEL UNCOMFORTABLE ENOUGH TO CURTAIL YOUR ACTIVITIES, REDUCE YOUR DOSAGE. If you are taking 3 caplets, reduce to 1 caplet. Do not stop taking the product! Just slow down so the toxin elimination is not so fast. Remember, if you are ill, the only way back to permanent health is to eliminate the cause of the disease, not to treat symptoms with drugs.

Primal Defense Clinical Study Results

Homeostatic soil organisms improve Candida, asthma, and other conditions in medically unresponsive chronic disease states. A physician skeptic performs the study…

Paul A. Goldberg, M.P.H., D.CIn January 2000, physician skeptic Paul A. Goldberg, M.P.H., D.C., professor of gastroenterology and public health at Life Chiropractic College, came across promotional materials about a probiotic product called Primal Defense™ containing homeostatic soil organisms thought to be as old as the earth itself; a number of patients had questioned him about this product. Dr. Goldberg is not a big fan of nutritional supplements. He believes the claims surrounding products all too often exaggerate their benefits. He therefore challenged Garden of Life, manufacturer, to allow him to do his own study utilizing a patient population that had been largely unresponsive to a wide range of medical treatments to see whether this formula could live up to its claims.* The completed study is scheduled to be published this fall in the peer-reviewed journal Progress in Nutrition.

Seventeen patients between 27 to 60 years of age, suffering from chronic diseases unresponsive to standard medical intervention for a minimum of three years, were given eighteen Primal Defense homeostatic soil organism (HSO) caplets per day for 120 days. Patients were evaluated by interview regarding their conditions pre- and post-administration of the Primal Defense caplets along with limited laboratory evaluation. At the termination of the study there were clinical improvements, of varying degrees, in subjects.

Scientific Validation for Primal Defense Soil Organisms
“Sixteen of seventeen subjects completing the study reported improvements in their symptoms including partial to complete relief from bowel problems, decreases in asthmatic symptomatology, increases in energy levels, improvement in skin conditions, improvement in chronic sinus infection and general improvements in overall well being,” notes Dr. Goldberg. “No subjects reported any worsening of their symptoms at the completion of the study.”

Notable Candida Yeast Reductions
Stool and/or blood testing before and after administration of Primal Defense revealed an appreciable lowering in Candida yeast counts in each of the eight subjects who showed elevated yeast counts initially. That is astounding! Every person with elevated Candida levels had a significant reduction. No subjects exhibited any significant increase in yeast counts. The results of the before and after stool microbiology’s were notable. Based on these samples, the HSOs in Primal Defense appear to be effective at reducing candida yeast growth, Dr. Goldberg notes. Two subjects had candida antibody titers done prior to and after the protocol. Both showed a significant reduction in their titers along with pronounced clinical improvement in their symptoms.

Notable Improvements among Asthmatics
Two subjects had a history of asthma with current symptomatology for which they were on prescription medications. Both of these subjects had a 50 percent or greater reduction in their asthmatic symptoms and in their usage of prescription inhalant medications upon completing the protocol. “Particularly notable was the reduction in asthmatic symptoms seen in two patents who had been asthmatic for many years,” notes Dr. Goldberg. “This is consistent with the ‘hygiene hypothesis,’ which suggests that the upsurge in childhood asthma has accompanied the decrease in bacterial exposure of modern children in industrialized societies and that through greater exposure to bacteria (and other microorganisms) a decrease in the incidence of asthma might be possible.”

Notable Improvements in Intestinal Conditions
Eleven of twelve subjects who initially experienced intestinal difficulties reported improvement in their overall bowel function consisting of one or more of the following types: relief from chronic constipation, less irritable bowel-type symptoms, reduced frequency of diarrhea, and greater ease in elimination without straining. None of the subjects reported any negative effects on bowel functioning.

Results Explained
“I have long recognized the importance of the gastrointestinal flora in good intestinal functioning and in regards to a wide variety of systemic health problems,” notes Dr. Goldberg. “Dietary modification, fasting, detoxification, lifestyle alterations, all are of positive impact on the gastrointestinal flora when properly applied; yet, with so many forces in our modern lives working against the maintenance of healthy gut flora I felt that additional reinforcement to the flora would be beneficial, particularly in clients with serious chronic health problems.”

Dr. Goldberg adds that it has been suggested as far back as the Russian embryologist and immunologist Élie Metchnikoff (1845-1916) that taking supplemental beneficial bacteria to reinforce and balance intestinal flora promotes intestinal well-being and produces systemic benefits. “Mounting epidemiological data and clinical studies support the idea that exposure to a wide variety of bacteria, as found in nature in the soil and general environment, play an important role in the development of healthy immune systems and the general state of resistance, to a wide variety of ailments. Conversely, a theory known as the ‘hygiene hypothesis’ suggests that many people in modern societies have been too highly protected from normal bacteria. This isolation from the bacteria in our environment, according to the ‘hygiene hypothesis,’ may contribute to the rise in chronic degenerative diseases such as asthma, inflammatory bowel disease, and a host of allergic conditions.

“It has been suggested that bacteria found in the soil, referred to as homeostatic soil organisms (HSOs) when ingested orally in a probiotic formulation, may have advantages over non HSO-probiotic formulas due to their ability to implant and survive in the gut. The value of HSOs reportedly lies in promoting positive intestinal function with corresponding systemic improvements in the patient’s overall nutritional, immunological and gastrointestinal status.

“It has been postulated that human beings ingested HSOs as part and parcel of the dietary intake prior to the sanitizing of food products as it occurs today in most Western nations. There is increasing evidence that our well-intended attempts at sanitizing our homes and food supply with antimicrobial cleaning solutions, disinfectants and soaps may be excessive and contributing to immune systems that do not develop healthy responses to outside influences. This lack of challenge to our immune systems is becoming increasingly suspect in regards to the increasing amounts of asthmatic children, raised under increasingly sanitary conditions, in the United States.

Individual Patient Results
Let’s look at the results first, see what kinds of conditions improved (if at all), and to what extent, and then let’s try to find the explanation for these results.

Subject 1 A 53-year old male with a 27-year medical history of progressive psoriatic arthritis and ulcerative colitis experienced symptomatic improvement during the first three weeks with improvements in bowel function and arthritic pains followed by an exacerbation with increases in joint inflammation and bloody diarrhea. His Primal Defense dosage was reduced from 18 to two caplets, two times per day, with a reduction of symptoms. The patient increased his dosage over the next several days, returning to 18 caplets per day, completing the 120-day protocol. He reported that his bowel function improved 25 percent by the end of the study with occasional days of “near normal stools,” which had not occurred for over five years. Improvements were also noted with less visible blood in his stool, better formed stools, and reduced incidence of cramping. There was no improvement in overall stiffness/joint discomforts. His sedimentation rate fluctuated, but, at the end of the study, remained close to what it had been at the start (55mm/hr). A follow up of the stool microbiology showed a significant reduction in the stool yeast count.

Subject 2 A 42-year-old female radiologist with a five-year history of chronic fungal infection of the lungs also had significant (approximately 25 percent) loss of lung function. She had chronic chest pain upon breathing. Long-term use of the anti-fungal drug Sporonox had not resolved the problem or allowed for any significant improvement. She also had chronic asthma and a significantly elevated serum yeast titer. At completion of the study, the subject reported feeling significant improvement. Her asthma symptomatology had improved by 70 percent, as rated by the subject. She reported greater ease in breathing, improved bowel function, and more energy. She had a reduction in chest pain and significant improvement in spirometer testing by her medical pulmonologist in January 2002. Yeast serum antibody testing performed on this subject at the completion of the study showed a marked drop in the titer from 900 to 438 U/ml. Therefore, it would appear that her infectious state had greatly improved, leading to improved lung function.

Subject 3 A 36-year-old male with chronic psoriasis widespread over his scalp, elbows, face, torso and legs improved with approximately 25 percent of the psoriatic lesions clearing and a lightening of the remaining affected areas.

Subject 4 A 46-year-old male with chronic irritable bowel syndrome since childhood that interfered with social and work activities, reported at the end of the protocol a reduction in symptoms of cramping / diarrhea / irritable bowel of approximately 25 to 30 percent.

Subject 5 A 57-year-old female with chronic diverticulitis, arthritis, and spinal degeneration, did not improve.

Subject 6 A 35-year-old female with chronic constipation of seven years duration and bowel movements that occurred once every three to four days, reported in the third week of the protocol that her constipation had abated entirely with bowel movements occurring every one to two days. She reported an enhanced sense of well being.

Subject 7 A 40-year-old male suffered from chronic fungal sinusitis of six years duration that had been unresponsive to medical treatments including allergy shots, antibiotics, and other drugs. The patient reported excellent response to the 120-day protocol, which was substantiated by examination of sinuses by his physician, an ear, nose and throat specialist. With the improvement of his sinuses, the patient also reported improvement in chronic fatigue that he had suffered from for approximately 10 years.

Subject 8 A 43-year-old female with chronic fatigue, constipation with laxative dependency, and depression, reported significant improvement in energy levels, reduction of depression, and complete relief from chronic constipation of five-plus year’s duration with her laxative dependency ended. (Prior to protocol, this patient reported having a bowel movement once every three days. After the protocol, the patient reported a daily bowel movement without laxative usage.)

Subject 9 A 43-year-old female with ulcerative colitis of five years duration, experienced an overall improvement in bowel function (approximately 33 percent as per subject) with reduced bleeding and cramping.

Subject 10 A 34-year-old female with systemic arthritis, joint and muscle pain and irritable bowel syndrome, found that at completion of the protocol she experienced a complete absence of “irritable bowel” symptoms and 75 percent reduction in joint/muscle pain (as per subject’s evaluation).

Subject 11 A 22-year-old female was medically diagnosed with rheumatoid arthritis, joint stiffness and general fatigue. She reported 75 percent improvement in joint stiffness and pain along with increased energy levels at completion of protocol. There was a decline in stool yeast growth, accompanied by drop in candida antibody serum titer from 1,688 to 183 u/ml.

Subject 12 A 40-year-old female with chronic diarrhea and fatigue found that after 40 days, her diarrhea completely abated and she experienced increased energy levels. Upon a follow-up examination after 80 days, she continued to report her bowel symptoms and energy improvement remained.

Subject 13 A 33-year-old female with chronic fatigue, indigestion and constipation, said she moved her bowels approximately once every 21 days. After 90 days, she reported that she was now having daily movements, accompanied by resolution of fatigue and digestive issues. A follow-up interview with the subject 30 days later showed she continued to remain well with absence of prior symptoms.

Subject 14 A 55-year-old female who had approximately one third of her colon removed three years earlier due to malignancy, had been experiencing intestinal distress with diarrhea for about three months. Following 60 days, she reported resolution of symptoms. She reported that she continued to remain symptom-free 60 days later.

Subject 15 A 35-year-old female had suffered chronic irritable bowel syndrome accompanied by cramping, diarrhea, and fatigue for over three years. Following 120 days, she reported a 50 to 75 percent symptomatic improvement in all symptoms. A follow-up of stool microbiology showed elimination of yeast in stool.

Subject 16 A 26-year-old male had a history of chronic nausea. Medical analysis/treatment had not been successful in alleviating the problem. Following 45 days, his nausea abated entirely. Upon follow-up 75 days later, his symptoms continued to be absent.

Subject 17 A 29-year-old female had chronic asthma. After 60 days, her asthma symptomatology had improved by 50 percent with a corresponding decrease in her prescription asthma medications.

“Anecdotal evidence suggests that a variety of chronic gastrointestinal, allergic, autoimmune and degenerative conditions can be positively affected by the consistent (three months or longer) administration of an HSO formulation.”

Diabetes Resource Centers Seal of Approval
Primal Defense has been awarded the Diabetes Resource Center’s “Seal of Approval” as a beneficial food for diabetic consumption.



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